The Department of Biotechnology (Instrumentation) focuses its teaching and research on equipment and processes for biotechnology and related medical technology. In the field of biophotonics, research is being conducted into radiation disinfection using UV or visible light to reduce Legionella or staphylococci, as well as the non-invasive, spectroscopic online determination of substance concentrations in bioreactor media. The bioreactors themselves, i.e. technical systems for the propagation and utilisation of microorganisms and cells, also form part of Apparative Biotechnology. The research group thus utilises and develops bioreactors for bacteria and fungi, as well as for cartilage tissue engineering, in which the required human cartilage tissue is grown from human cells.
Project manager: Prof. Dr. Jörg Moisel
Project duration: 01.04.2023 - 31.03.2026
Funded by: Federal Government - BMWK
Program name: ZIM - R&D cooperation project
Project description:
The aim of the project is to develop a novel LED therapy lamp with multiple emission wavelengths for the evidence-based treatment of skin diseases using photodynamic therapy with the aid of HSI and cloud-based healing control. The main areas of application are actinic keratosis, a precursor of skin cancer, and the treatment of severe acne, in the development of which Cutibacterium acne plays an important role. The modular treatment device to be created,
, will contain completely new technological functionalities, in which for the first time the relationship between radiation parameters and evidence of treatment will be recognizable, controllable and documentable. It also has sophisticated LED lighting parameters and sensor-supported systems for distance measurement, cooling and treatment control.
Project manager: Prof. Dr. Martin Heßling
Project duration: 01.10.2023 - 30.09.2025
Funded by: Federal Government - BMBF
Program name: KMU-Innovativ
Project description:
The aim of the project is to develop a demonstrator for a blue/violet luminescent endotracheal tube to prevent ventilator-associated pneumonia (VAP) - one of the most common nosocomial infections. VAPs occur during prolonged ventilation in intensive care units and lead to a significant extension of the patient's stay, 5-digit additional costs per individual case and often even to the death of the patient, as they are usually antibiotic-resistant pathogens. The approach planned here is based on the antimicrobial effect of short-wave, visible light. The aim is to develop an optical fiber-based illumination system that illuminates the area around the cuff of commercially available ventilation tubes with blue or violet light of sufficient intensity and inactivates pathogens outside and inside the tube without damaging the tracheal tissue. The resulting prevention of VAPs leads to an enormous reduction in the burden on the healthcare system, a reduction in deaths as a result of artificial ventilation and an improvement in the patient's quality of life. In addition, new antibiotic resistances can be avoided.
Project manager: Prof. Dr. Martin Heßling
Project duration: 01.06.2021 - 31.05.2023
Funded by: Federal Government - BMWK
Program name: ZIM - R&D cooperation project
Project description:
The aim of the project is to research and develop a touchscreen unit with integrated antimicrobial treatment and disinfection of the screen using LED radiation for installation in self-service terminals (ticket machines, EC terminals, etc.).
The current global pandemic has highlighted the importance of implementing hygiene measures. One object that many people touch every day are touchscreens on ticket machines, for example, which are a breeding ground for bacteria and other harmful germs due to their surface temperature. The aim of the project is to develop a disinfection process for flat and curved surfaces. CleanScreen is an innovative touchscreen unit (16:9) with integrated disinfecting light (e.g. UV radiation 200-450nm), which penetrates the user surface from behind and kills germs, thus reducing the risk of infection for the user. Penetration of the screen is to be achieved by coupling the antimicrobial light from the side using optical fibres with an evanescent field.
Project manager: Prof. Dr. Martin Heßling
Project duration: 01.04.2019 - 31.01.2023
Funded by: Federal Government - BMBF
Project description:
In view of the increase in antibiotic resistance, combating bacterial infections is one of the most important medical issues. In Germany, for example, around 420,000 people are infected every year with the often particularly resistant "hospital germs", of which methicillin-resistant Staphylococcus aureus is the best known, but not the only one. These infections lead to longer hospital stays, higher costs and, in an estimated 7,500 cases in Germany alone, death every year. In intensive care units, artificial respiration most frequently leads to such infections. The patient is given a breathing tube that remains in the windpipe for days or weeks. During this time, pathogens can multiply on the inside or outside of the tube, migrate into the lungs and cause infections there. In the project presented here, a ventilation tube with miniature LEDs in the tube wall that disinfects itself and its surroundings with visible light is to be developed following basic research. This means that the dreaded pathogens should be killed before they reach the lungs and human cells should not be damaged in the process.
Project manager: Prof. Dr. Martin Heßling
Project duration: 01.05.2020 - 31.10.2022
Funded by: Federal Government - BMWi
Program name: ZIM
Project description: The project aims to develop a process to control microbial contamination in the powder coating process chain. A process and corresponding plant technology is to be developed that allows safe, reliable control of the various types of contamination, ensures optimum functionality of the powder coating without compromising the quality of the coating result and leads to significant cost savings compared to the current situation. The process to be developed for this purpose should include the control of ("free") microorganisms in the process solution, the prevention or control of biofilm formation on the walls of the process baths and the detection of microorganisms and biofilm for reliable monitoring of the system as essential solution components.
Project manager: Prof. Dr. Martin Heßling
Project duration: 01.10.2016 - 31.12.2020
Funded by: Federal Government - BMWi
Program name: ZIM
Project description: As part of this project between Ulm University of Applied Sciences, Pharmpur GmbH (Königsbrunn) and Epigap Optronik GmbH (Berlin) & Co. KG (Dornstadt) are developing new lighting concepts for retinal surgery with the support of the Frankfurt University Eye Hospital, which are gentler and cheaper than conventional lighting systems. In contrast to previous systems, the new LED endoilluminators even manage without injuring the eye in some cases. More uniform illumination of the inside of the eye is achieved, while at the same time greatly reducing the risk to the retina from thermal or photochemical processes.
Project manager: Prof. Dr. Martin Heßling
Project duration: 01.05.2018 - 31.05.2020
Funded by: Federal Government - BMWi
Program name: ZIM
Project description: Drinking water in emerging countries is often highly contaminated and pure water is hardly available there. Current disinfection systems with Hg lamps are not very energy-efficient and are not suitable for use in emerging countries (risk of mercury poisoning). At turbidity levels above 5-10 NTU, their decontamination capability also fails. The aim of the system shown is to remove microorganisms and pathogenic germs from >500 l/h of process water (equivalent to 20-100 times the output of previous LED water disinfection systems) with a turbidity level of up to 200 NTU. The water is to be cascaded through the bottom particle filters and further treated in the UV-C LED passage without the use of pumps. Biofilm-inhibiting materials (e.g. treated copper elements) are intended to prevent the formation of germ nests. A novel control system is designed to adaptively control the power of the LEDs (up to 1000mW) and the flow rate (detour if necessary) in the reactor so that even after the bottom passage, turbid water >10NTU is still optimally sterilized. A downstream, newly developed XYLEM filter is intended to further treat the purified water for high demands (infants).
Project manager: Prof. Dr. Martin Heßling
Project duration: 01.03.2015 - 20.06.2019
Funded by: Stiftung
Program name: Cusanus-Stipendium
Project description: An approach for improved contact lens disinfection was found that is gentler on the eye of the contact lens wearer by dispensing with aggressive reagents and, on the other hand, promises even greater disinfection success. This approach is based on the antimicrobial effect of violet radiation, which causes porphyrins in bacteria to form aggressive radicals that destroy the bacteria from the inside. This idea is being investigated in more detail in Ms. Hönes' doctoral thesis, both with regard to its disinfection effectiveness against contact lens-relevant germs and with a view to possible changes to the contact lens.
Ms. Hönes has already won two prizes for her work:
Project manager: Prof. Dr. Martin Heßling
Project duration: 01.09.2013 - 31.12.2019
Project description: In this project, a bioreactor system with online optical monitoring for the growth of human cartilage tissue is being developed. Specifically, it is about the replacement of cartilage tissue in the neck and head area, for example when cartilage tissue of the auricles, nose or trachea is destroyed by accident or disease. Ideally, the replacement tissue should have the same properties as the original and be tolerated by the body. The best way to achieve this is to grow it from the patient's own cells. This so-called tissue engineering takes place in a bioreactor supplied with nutrients and oxygen. This is equipped with a three-dimensional scaffold on which the cells can grow, multiply and form a stable tissue structure. During the process, which can take days to weeks, the environment must be kept germ-free and stable. Non-destructive monitoring and quality control is not possible with the commercial bioreactors used for the extraction of articular cartilage. This is where Professor Hessling's project comes in. The new bioreactor system should enable the controlled and optimized production of cartilage tissue. Cartilage quality and cell differentiation are to be assessed non-destructively using spectral data and the growth environment of the cells is to be continuously recorded using special online analytics and optimized based on this data. This approach is particularly important for the re-growth of cartilage tissue in the trachea, because in addition to cartilage cells, epithelial cells, which require different conditions for their proliferation, must also grow into the cell structure. The tests with appropriate cell material required for the development of the system will be carried out in Professor Dr. Nicole Rotter's working group at the Department of Otorhinolaryngology at Ulm University Hospital. For his master's thesis on the spectral camera, Mr. Artur Kühn won the VDI Prize of the 2015 summer semester at Ulm University of Applied Sciences.
Project manager: Prof. Dr. Martin Heßling
Project duration: 01.06.2015 - 31.05.2017
Project description: The aim of the project is to develop a compact biofilm reactor that is to be integrated into drinking water systems upstream of domestic connections in the medium term. This additional biofilm reactor is intended to remove nutrients (organic compounds, nitrogen compounds and phosphate compounds) from drinking water in order to starve existing biofilms in domestic installations and reduce the germ load at the end consumer. In addition, a technical system for detecting the formation of new biofilms using spectroscopic approaches is to be developed.
Project manager: Prof. Dr. Martin Heßling
Project duration: 01.09.2013 - 29.02.2016
Project description: The aim of the project is to develop a compact, low-cost, maintenance-free and energy self-sufficient water disinfection system. Within this system, UVC LEDs are to be used, which on the one hand are ideally suited for the disinfection of water containing germs and on the other hand are characterized by a long service life, a certain robustness and extremely low energy consumption. This should be so low that the entire disinfection system can be operated with a so-called picosolar system, consisting of a solar cell and battery. This makes it possible to use the water disinfection system on the move and independently of the availability of a power grid, which increases the potential areas of application immensely.
The employees won a poster prize as part of this project: Felix Stangl, Katharina Hönes, Andrej Gross and Marc Miller, 1st prize in the poster competition "4th Symposium Small PV Applications & Intersolar Europe" with the poster Photovoltaic Based Water Disinfection System, Munich, June 2015.
Project manager: Prof. Dr. Martin Heßling
Project duration: 01.03.2013 - open
Project description:As part of a cooperation between Ulm University of Applied Sciences and alamedics GmbH & Co. KG (Dornstadt), new lighting concepts for retinal surgery were developed with the support of the Frankfurt University Eye Hospital, which are gentler and cheaper than conventional lighting systems. In contrast to previous systems, the non-invasive LED endoilluminator presented here does not require injury to the eye. It achieves more uniform illumination of the inside of the eye, while at the same time greatly reducing the risk to the retina from thermal or photochemical processes.
Together with the project partners, a major European prize was awarded for this idea: Christian Lingenfelder (Alamedics GmbH), Frank Koch (University Hospital Frankfurt) and Martin Heßling, Euretina Innovation Award for the development of new LED illumination approaches for retinal surgery, Nice, September 2015.
Project manager: Prof. Dr. Martin Heßling
Project duration: 01.09.2011 - 31.08.2015
Project description: The aim of the "BIOsens" cooperation project is to develop an optical online measurement system that determines glucose and ethanol, among other things, using their physical and optical properties. The optical system should consist of at least one light source, light guides, a probe and at least one spectrometer. In addition, there will be a PC and software to convert the optical measurement data into the concentrations of the various substances. The sensor to be developed will be used to carry out a continuous (online) absorption measurement of the substances of interest and to determine the concentration of the substances in the fermenter broth using a chemometric method. The main users and purchasers of the BIOsens system are research laboratories. However, there is a need for such a sensor system not only in biotechnology, but also in neighboring areas such as the food industry.
Akrah, Aya; Hessling, Martin:
Investigation into the feasibility of a lightguide based prevention of catheterassociated urinary tract infections (CAUTI),
in: Current Directions in Biomedical Engineering, vol. 10, no. 4, Deutsche Gesellschaft für Biomedizinische Technik, 2024, de Gruyter, pages 17-20.
DOI: 10.1515/cdbme-2024-2005
ISSN: 2364-5504
Bekawi, Dima; Gierke, Anna-Maria; Hasan, Sameer Ahmad; Al-Zyoud, Walid; Hessling, Martin:
Photoinactivation of Streptococcus cristatus and Streptococcus vestibularis by 222 and 254 nm UVC Irradiation,
in: Acta Microbiologica Bulgarica Vol. 40/4, Bulgarian Society for Microbiology, 2024, pp. 563-567.
DOI: 10.59393/amb24400416 / ISSN: 0204-8809
Deuschl, Sebastian; Sicks, Ben; Moritz, Helge; Hessling, Martin:
Prototype of a Public Computer System with Fast Automatic Touchscreen Disinfection by Integrated UVC LEDs and Total Reflection,
in: Physical Sciences Forum. 2024; 10(1):3, MDPI, 2024, pages 7.
DOI: 10.3390/psf2024010003
ISSN: 2673-9984
Fehler, Nicole; Haag, Robin; Messias, André; Hessling, Martin:
Fast and Mobile Cataract Detection by Applying Line Laser Eye Illumination,
in: Jurnal Teknokes 17 (1), 1-7, Department of Medical Electronics Technology, Health Polytechnic of Surabaya, Ministry of Health Indonesia, 2024, pages 1-7.
DOI: 10.35882/teknokes.v17i1.639
ISSN: 2407-8964
Gierke, Anna-Maria; Hessling, Martin:
Photoinactivation by UVA radiation and visible light of Candida auris compared to other fungi,
in: Photochemical & Photobiological Sciences 2024, Volume 23, European Society for Photobiology and the European Photochemistry Association, Springer Nature, 2024, pages 12 (681-692).
DOI: 10.1007/s43630-024-00543-4
ISSN: 1474-9092
Gierke, Anna-Maria; Hessling, Martin:
Sensitivity Analysis of C. auris, S. cerevisiae, and C. cladosporioides by Irradiation with Far-UVC, UVC, and UVB,
in: Pathogens and Immunity 2024, vol.9, no.2, Case Western Reserve University (Cleveland, Ohio), 2024, pages 135-151.
DOI: 10.20411/pai.v9i2.723
ISSN: 2469-2964
Gierke, Anna-Maria; Vatter, Petra; Hessling, Martin:
Fungalphotoinactivation doses for UV radiation and visible light-a data collection,
in: AIMS Microbiology, Vol. 10, Issue 3, AIMS Press, 2024, pages 694-722.
DOI: 10.3934/microbiol.2024032
ISSN: 2471-1888
Noller, Kilian; Sicks, Ben; Hessling, Martin:
One-Second Touchscreen Disinfection with Internal UVC-LEDs,
in: Photonics 2024; 11(11):1001, MDPI, 2024, pages 11.
DOI: 10.3390/photonics11111001
ISSN: 2304-6732
Sicks, Ben; Gurow, Oksana; Sommerfeld, Florian; Hessling, Martin:
Decontamination of Fused-Silica Surfaces by UVC Irradiation as Potential Application on Touchscreens.
in: Microorganisms 2024; 12(10):2099, MDPI, 2024, pages 1-12.
DOI: 10.3390/microorganisms12102099
ISSN: 2076-2607
Sicks, Ben; Gurow, Oksana; Hessling, Martin:
Future Disinfection of Touch Screens by Far-UVC-LEDs?-A Feasibility Study,
in: IEEE Photonics Technology Letters, Volume 36, Issue 16, IEEE, 2024, Pages 981 - 984.
DOI: 10.1109/LPT.2024.3422903
ISSN: 1941-0174
Sicks, Ben; Maiss, Florian; Lingenfelder, Christian; Wiegand, Cornelia; Hessling, Martin:
Comparison of Different Far-UVC Sources with Regards to Intensity Stability, Estimated Antimicrobial Efficiency and Potential Human Hazard in Comparison to a Conventional UVC Lamp,
in: Physical Sciences Forum. 2024; 10(1):1, MDPI, 2024, pages 8.
DOI: 10.3390/psf2024010001
ISSN: 2673-9984
Sommerfeld, Florian; Weyersberg, Laura; Vatter, Petra; Hessling, Martin:
Photoinactivation of the bacteriophage PhiX174 by UVA radiation and visible light in SM buffer and DMEM-F12,
in: BMC Res Notes 17, 3 (2024), Springer Nature, 2024, pages 1-7.
DOI: 10.1186/s13104-023-06658-8
ISSN: 1756-0500
Enders, Christian; Klante, Pia; Hessling, Martin; Wolf, Armin; Werner, Jens Ulrich:
Reutilization of disposable rebound tonometer probes Risk or return,
in: Indian Journal of Ophthalmology 71(5):p 1932-1936, May 2023, All India Ophthalmological Society, Wolters Kluver, 2023, pages 1932-1936.
DOI: 10.4103/ijo.IJO_1790_22 ISSN: 0301-4738
Fehler, Nicole; Lingenfelder, Christian; Hessling, Martin; Kupferschmid, Sebastian:
Retinal risk of endoillumination: A comparison of different ophthalmic illumination systems,
in: Journal Français d'Ophtalmologie, 2023, French Society of Ophthalmology, Elsevier, 2023, pages 1-12.
DOI: doi.org/10.1016/j.jfo.2022.10.007
ISSN: 0181-5512
Fehler, Nicole; Lingenfelder, Christian; Kupferschmid, Sebastian; Hessling, Martin:
Determination of the intraocular irradiance and potential retinal hazards at various positions in the eye during transscleral equatorial illumination for different applied pressures,
in: Zeitschrift für Medizinische Physik 2022 (online), German and Austrian Society of Medical Physics and the Swiss Society of Radiobiology and Medical Physics, Elsevier, 2023, pages 1-10.
DOI: 10.1016/j.zemedi.
Fehler, Nicole; Hessling, Martin:
LuminousFlux in Ex-Vivo Porcine Eyes during Endoillumination and during Transscleral Illumination Depending on the Transmission Properties of the Eyewall,
in: Photonics 2023, 10(4), 362, MDPI, MDPI, 2023, pages 1-10.
DOI: 10.3390/photonics10040362
ISSN: 2304-6732
Fehler, Nicole; Hessling, Martin:
Determination of Correlated Color Temperature in Ex Vivo Porcine Eyes during Intraocular Illumination,
in: Journal of Clinical Medicine, 2023, The International Bone Research Association (IBRA), Italian Resuscitation Council (IRC), Spanish Society of Hematology and Hemotherapy (SEHH), Japan Association for Clinical Engineers (JACE), European Independent Foundation in Angiology/ Vascular Medicine, MDPI, 2023, pages 1-12.
DOI: 10.3390/jcm12083034
ISSN: 2077-0383
Fehler, Nicole; Schneider, David; Hessling, Martin:
Advancement of a RGBW-LED pen for diaphanoscopic illumination with adjustable color and intensity with tests on ex-vivo porcine eyes in terms of retinal risk and correlated color temperature,
in: Biomed. Eng. Lett. (2023), Korean Society of Medical and Biological Engineering, Springer, Heidelberg, 2023, pages 1-12.
DOI: 10.1007/s13534-023-00317-4
ISSN: 2093-985X
Fischer, Simone; Fehler, Nicole; Hessling, Martin:
Feasibility study for a possible therapy of bacterial keratitis by UVB irradiation,
in: Current Directions in Biomedical Engineering, vol. 9, no. 1, 2023, Joint Journal of the German Society for Biomedical Engineering in VDE and the Austrian and Swiss Societies for Biomedical Engineering, De Gruyter, 2023, pages 45-48.
DOI: 10.1515/cdbme-2023-1012
ISSN: 2364-5504
Gierke, Anna-Maria; Lingenfelder, Christian; Hessling, Martin:
Investigation in the antimicrobial impact of cold plasma on wet and dry microorganisms,
in: Biol. Life Sci. Forum 2023, Vol. 31 (ECM-2023), MDPI, Pages 1-6 (Article No. 16475)
DOI: 10.3390/ECM2023-16475
ISSN: 2673-9976
Hessling, Martin; Sicks, Ben; Gierke, Anna-Maria; Haag, Robin; Lau, Bernhard:
Assessment of visible violet light for hand disinfection,
in: Biol. Life Sci. Forum 2023, Vol. 31 (ECM-2023), MDPI, pages 1-6 (Article No. 16455)
DOI: 10.3390/ECM2023-16455
ISSN: 2673-9976
Hessling, Martin; Sicks, Ben; Lau, Bernhard:
Far-UVC Radiation for Disinfecting Hands or Gloves,
in: Pathogens 2023, 12(2), 213, MDPI, 2023, pages 6.
DOI: doi.org/10.3390/pathogens12020213
ISSN: 2076-0817
Nuding, Katharina; Lotfi, Ramin; Radermacher, Peter; Spellerberg, Barbara; Buehler, Jule; Sicks, Ben; Hoenes, Katharina; Hessling, Martin:
Basic studies on the influence of hemorrhage on the antimicrobial effect of visible light in a trachea model,
in: Current Directions in Biomedical Engineering, vol. 9, no. 1, 2023, Joint Journal of the German Society for Biomedical Engineering in VDE and the Austrian and Swiss Societies for Biomedical Engineering, De Gruyter, 2023, pages 307-310.
DOI: 10.1515/cdbme-2023-1077
ISSN: 2364-5504
Schinko, Quirin; Niznik, Jessica; Runke, Alex Randy; Heßling, Martin; Gierke, Anna-Maria:
Photoinactivation of E. coli on bagged Valerianella locusta and on Cichorium intybus var. foliosum with 222 and 254 nm,
in: Biol. Life Sci. Forum 2023, Vol. 31 (ECM-2023), MDPI, pages 1-6 (Article No. 16466)
DOI: 10.3390/ECM2023-16466
ISSN: 2673-9976
Sicks, Ben; Gierke, Anna-Maria; Sommerfeld, Florian; Klein, Martin; Hessling, Martin:
Disinfection of Transparent Screens by Side-Coupled UVA LED Radiation,
in: Optics, 4(2):321-329, 2023, MDPI, MDPI, 2023, pages 321-329.
DOI: doi.org/10.3390/opt4020023
ISSN: 2673-3269
Sommerfeld, Florian; Osswald, Patricia; Weller, Pia; Hessling, Martin:
Photoinactivation of Staphylococcus carnosus on surfaces by irradiation with blue and violet light,
in: Biol. Life Sci. Forum 2023, Vol. 31 (ECM-2023), MDPI, Pages 1-6 (Article No. 16474)
DOI: 10.3390/ECM2023-16474
ISSN: 2673-9976
Weyersberg, Laura; Sommerfeld, Florian; Vatter, Petra; Hessling, Martin:
UV radiation sensitivity of bacteriophage PhiX174 - A potential surrogate for SARS-CoV-2 in terms of radiation inactivation,
in: AIMS Microbiology, 2023, 9(3), AIMS Press, 2023, pages 431-443.
DOI: 10.3934/microbiol.2023023
ISSN 2471-1888
Fehler, Nicole; Lingenfelder, Christian; Kupferschmid, Sebastian; Hessling, Martin:
Intraocular reflectance of the ocular fundus and its impact on increased retinal hazard,
in: Zeitschrift für Medizinische Physik, Volume 32, Issue 4, 2022, German and Austrian Society of Medical Physics and the Swiss Society of Radiobiology and Medical Physics, Elsevier, 2022, pages 453-465.
DOI: 10.1016/j.zemedi.2022.03.001
ISSN 0939-3889
Fehler, Nicole; Lingenfelder, Christian; Kupferschmid, Sebastian; Hessling, Martin:
Determination of the intraocular irradiance and potential retinal hazards at various positions in the eye during transscleral equatorial illumination for different applied pressures,
in: Zeitschrift für Medizinische Physik 2022, German and Austrian Society of Medical Physics and the Swiss Society of Radiobiology and Medical Physics, Elsevier, 2022, pages 10.
DOI: 10.1016/j.zemedi.2022.11.005
ISSN 0939-3889
Gierke, Anna-Maria; Hessling, Martin:
Investigation on Potential ESKAPE Surrogates for 222 and 254 nm Irradiation Experiments,
in: Frontiers in Microbiology, vol. 13, article 942708, Frontiers, 2022, pages 11.
DOI: 10.3389/fmicb.2022.942708
ISSN 1664302X
Hessling, Martin; Fehler, Nicole; Gierke, Anna-Maria; Sicks, Ben; Vatter, Petra:
Heat Inactivation of Influenza Viruses-Analysis of Published Data and Estimations for Required Decimal Reduction Times for Different Temperatures and Media,
in: Microbiology Research, 13(4), MDPI, 2022, pages 853-871.
DOI: 10.3390/microbiolres13040060
ISSN: 2036-7481
Hessling, Martin; Gierke, Anna-Maria; Sicks, Ben; Fehler, Nicole; Vatter, Petra:
Sensitivity of influenza virus to ultraviolet irradiation,
in: GMS Hygiene and Infection Control 2022, Vol. 17:Doc20, German Society for Hospital Hygiene (DGKH), GMS, 2022, pages 9.
DOI: 10.3205/dgkh000423
ISSN: 2196-5226
Hessling, Martin; Lau, Bernhard; Vatter, Petra:
Review of Virus Inactivation by Visible Light,
in: Photonics. 2022; 9(2):113, MDPI, 2022, pages 11.
DOI: 10.3390/photonics 9020113
ISSN: 2304-6732
Hessling, Martin; Meurle, Tobias; Hoenes, Katharina:
Surface disinfection with white-violet illumination device,
in: AIMS Bioengineering 2022, Volume 9, Issue 2, AIMS Press, 2022, pages 93-101.
DOI: 10.3934/bioeng.2022008
ISSN: 2375-1495
Heßling, Martin; Meurle, Tobias; Hönes, Katharina:
The disinfecting effect of white light,
in: Licht 3 / 2022, German Lighting Technology Society (LiTG) and Lighting Standards Committee (FNL) at DIN Deutsches Institut für Normung e.V., Richard Pflaum Verlag, 2022, pages 62-65.
Weyersberg, Laura; Klemens, Eva; Buehler, Jule; Vatter, Petra; Hessling, Martin:
UVC, UVB and UVA susceptibility of Phi6 and its suitability as a SARS-CoV-2 surrogate,
in: AIMS Microbiology, 8 (3), AIMS, AIMS Press, 2022, pages 278-291.
DOI: 10.3934/microbiol.2022020
ISSN 2471-1888
Zeller, Katja; Mühleisen, Stephan; Shanmugarajah, Pranavi; Fehler, Nicole; Haag, Robin; Hessling, Martin:
Influence of Visible Violet, Blue and Red Light on the Development of Cataract in Porcine Lenses,
in: Medicina 2022, 58(6), 721, Lithuanian Medical Association, MDPI, 2022, pages 1-10.
DOI: 10.3390/medicina58060721
ISSN: 1648-9144
Bauer, R., Hoenes, K., Meurle, T., Hessling, M., Spellerberg, B.:
The effects of violet and blue light irradiation on ESKAPE pathogens and human cells in presence of cell culture media,
in: Scientific Reports 11, 24473 (2021), Springer Nature, Springer Nature, 2021, pages 11.
DOI: 10.1038/s41598-021-04202-x
ISSN: 2045-2322
Buehler, Jule; Sommerfeld, Florian; Meurle, Tobias; Hoenes, Katharina; Hessling, Martin:
Disinfection Properties of Conventional White LED Illumination and Their Potential Increase by Violet LEDs for Applications in Medical and Domestic Environments,
in: Advances in Science and Technology Research Journal 2021, 15(2), 169-175, Polish Academy of Sciences (PAN), Polish Academy of Sciences (PAN), 2021, pages 169-175.
DOI: 10.12913/22998624/134641
ISSN: 2299-8624
Busshardt, Johannes; Sieber, Nicole; Koelbl, Philipp; Lingenfelder, Christian; Hessling, Martin:
Development and first assessment of a RGBW-LED diaphanoscope,
in: Ophthalmology Journal, Vol. 6, 2021, The Polish Association of Ophthalmic Surgeons.., VM Media sp. z o.o. VM Group sp.k., Grupa Via Medica, 2021, pages 101-106.
DOI: 10.5603/OJ.2021.0020
e-ISSN: 2450-9930
Goldberg-Bockhorn, Eva; Wenzel, Ulla; Theodoraki, Marie-Nicole; Döscher, Johannes; Riepl, Ricarda; Wigand, Marlene C.; Brunner, Cornelia; Heßling, Martin; Hoffmann, Thomas K.; Kern, Johann; Rotter, Nicole:
Enhanced cellular migration and prolonged chondrogenic differentiation in decellularized cartilage scaffolds under dynamic culture conditions,
in: Journal of Tissue Engineering and Regenerative Medicine 2021, John Wiley and Sons Ltd, Wiley, 2021, pages 15.
DOI: 10.1002/term.3261
ISSN: 1932-7005
Haag, Robin; Sieber, Nicole; Hessling, Martin:
Cataract Development by Exposure to Ultraviolet and Blue Visible Light in Porcine Lenses,
in: Medicina 2021, 57(6), 535, Lithuanian University of Health Sciences, MDPI, 2021, pages 1-11.
DOI: 10.3390/medicina57060535
ISSN: 1648-9144
Hessling, Martin; Haag, Robin; Sieber, Nicole; Vatter, Petra:
The impact of far-UVC radiation (200-230 nm) on pathogens, cells, skin, and eyes - a collection and analysis of a hundred years of data,
in: GMS Hygiene and Infection Control 2021;16:Doc07, Deutsche Gesellschaft für Krankenhaushygiene, German Medical Science, 2021, pages 17.
DOI: 10.3205/dgkh000378
ISSN: 2196-5226
Hessling, Martin; Haag, Robin; Sicks, Ben:
Review of microbial touchscreen contamination for the determination of reasonable ultraviolet disinfection doses,
in: GMS Hygiene and Infection Control 2021;16:Doc30, Deutsche Gesellschaft für Krankenhaushygiene, German Medical Science, 2021, pages 1-9 (+12 pages appendix).
DOI: 10.3205/dgkh000401
ISSN: 2196-5226
Hoenes, Katharina; Bauer, Richard; Meurle, Tobias; Spellerberg, Barbara; Hessling, Martin:
Inactivation Effect of Violet and Blue Light on ESKAPE Pathogens and Closely Related Non-pathogenic Bacterial Species - A Promising Tool Against Antibiotic-Sensitive and Antibiotic-Resistant Microorganisms,
in: Frontiers in Microbiology, Volume 11 (online), 2021, Frontiers Research Foundation, Frontiers, 2021, Pages 11.
DOI: 10.3389/fmicb.2020.612367
ISSN: 1664-302X
Katharina Hoenes, Richard Bauer, Barbara Spellerberg, Martin Hessling:
Microbial Photoinactivation by Visible Light Results in Limited Loss of Membrane Integrity,
in: Antibiotics 2021, 10(3), 341, MDPI, MDPI, 2021, pages 15.
DOI: 10.3390/antibiotics10030341
ISSN: 2079-6382
Knaus, Johannes; Vatter, Petra; Hessling, Martin:
Development and verification of a test rig for inactivation of bacteria and (corona-) viruses by UVC air disinfection systems,
in: Current Directions in Biomedical Engineering 2021;7(2):, DeGruyter, DeGruyter, 2021, pages 315-318.
DOI: 10.1515/cdbme-2021-2080
ISSN: 2364-5504
Lau, Bernhard; Becher, Dietmar; Hessling, Martin:
High Intensity Violet Light (405 nm) Inactivates Coronaviruses in Phosphate Buffered Saline (PBS) and on Surfaces,
in: Photonics 2021, 8(10), MDPI, MDPI, 2021, pages 9.
DOI: 10.3390/photonics8100414
ISSN: 2304-6732
Meurle, Tobias; Knaus, Johannes; Barbano, Agustin; Hoenes, Katharina; Spellerberg, Barbara; Hessling, Martin:
Photoinactivation of Staphylococci with 405 nm Light in a Trachea Model with Saliva Substitute at 37 °C,
in: Healthcare 2021, 9(3), 310, MDPI, MDPI, 2021, pages 1-13.
DOI: 10.3390/healthcare9030310
ISSN: 2227-9032
Sicks, Ben; Stock, Christina; Peter, Sarah; Meurle, Tobias; Hoenes, Katharina; Spellerberg, Barbara; Hessling, Martin:
Minimum irradiance required to inhibit microbial growth to prevent ventilatorassociated pneumonia by an endotracheal tube equipped with blue LEDs,
in: Current Directions in Biomedical Engineering 2021;7(2), Deutsche Gesellschaft für Biomedizinische Technik, DeGruyter, 2021, pages 239-242.
DOI: 10.1515/cdbme-2021-2061
ISSN: 2364-5504
Sieber, Nicole; Lingenfelder, Christian; Götz, Madeleine; Heine, Pauline; Lichtner, Leonie; Kupferschmid, Sebastian; Hessling, Martin:
Vitrectome with Integrated LED Illumination: Development and Testing,
in: Current Directions in Biomedical Engineering 2021;7(2), Deutsche Gesellschaft für Biomedizinische Technik, De Gruyter, 2021, pages 851-854.
DOI: 10.1515/cdbme-2021-2217
ISSN: 2364-5504
Vatter, Petra; Hoenes, Katharina; Hessling, Martin:
Blue light inactivation of the enveloped RNA virus Phi6,
in: BMC Research Notes, 14:187, 2021, BiomedCentral, BiomedCentral. Part of Springer Nature, 2021, pages 5.
DOI: 10.1186/s13104-021-05602-y
ISSN: 1756-0500
Heßling, Martin; Hönes, Katharina; Meurle, Tobias; Knaus, Johannes; Sicks, Ben; Bauer, Richard; Spellerberg, Barbara:
Luminescent, LED-based endotracheal tubes against pneumonia,
in: Photonics Flashlight Issue 1, June 2021, Phototonics Hub / Optence e.v., Phototonics Hub / Optence e.v., 2021, pages 12-15.
Hessling, Martin; Haag, Robin; Fehler, Nicole; Sicks, Ben; Gierke, Anna-Maria; Vatter, Petra:
Far-UVC - The UV radiation of the future?
in: LABO (Labor-Fachzeitschrift), issue 11, 2021, 53rd year, WEKA BUSINESS MEDIEN GmbH, WEKA BUSINESS MEDIEN GmbH, 2021, pages 42-47.
ISSN: 0344-5208
Hildebrandt, Christian; Lingenfelder, Christian; Sieber, Nicole; Kölbl, Philipp; Koch, Frank; Hessling, Martin:
Development of a Miniature Chip-On-Tip Intraocular Endoscope,
in: European Conferences on Biomedical Optics (online conference proceedings), June 2021, Optical Society of America / Society of Optical Engineers, Optica, 2021, pages 1-3 (EW4A.11).
Knaus, Johannes; Vatter, Petra; Hessling, Martin:
Effect and test of UVC air disinfection systems,
in: Hygiene-Report 5/2021, Publisher: Benno Keller, Dr. Harnisch Verlags GmbH, 2021, pages 14-17.
ISSN: 1618-2456
Hessling, M.; Hoenes, K.; Vatter, P.; Lingenfelder, C.:
Ultraviolet irradiation doses for coronavirus inactivation - review and analysis of coronavirus photoinactivation studies,
in: GMS - Hygiene and Infection Control, 2020; 15.
doi: 10.3205/dgkh000343
Vatter, Petra; Hönes, Katharina; Hessling, Martin:
Photoinactivation of the Coronavirus Surrogate phi6 by Visible Light,
in: Photochemistry and Photobiology - so far only online, American Society for Photobiology (ed.), Wiley, 2020, pages 4.
DOI: 10.1111/php.13352, ISSN:1751-1097
Koelbl, P. S.; Sieber, N.; Lingenfelder, C.; Koch, F.; Deuchler, S.; Hessling, S.:
Pressure dependent direct transtissue transmission of eyewall, sclera and vitreous body in the range of 350-1050 nm,
in: Zeitschrift fur Medizinische Physik (Journal of Medical Physics), March 2020, aop.
doi: 10.1016/j.zemedi.2020.02.003
Hessling, Martin; Hönes, Katharina; Lingenfelder, Christian:
Selection of parameters for thermal coronavirus inactivation - a data-based recommendation,
in: GMS Hygiene and Infection Control, 15, 2020, Deutsche Gesellschaft für Krankenhaushygiene (ed.), GMS, 2020, pages 7 + appendix.
DOI: 10.3205/dgkh000351, ISSN: 2196-5226
Hönes, Katharina; Spellerberg, Barbara; Hessling, Martin:
Enhancement of Contact Lens Disinfection by Combining Disinfectant with Visible Light Irradiation,
in: International Journal of Environmental Research and Public Health, 2020, 17(17), 6422, MDPI (ed.), MDPI, 2020, pages 20.
DOI: doi.org/10.3390/ijerph17176422, ISSN: 1660-4601
Hessling, Martin; Wenzel, Ulla; Meurle, Tobias; Spellerberg, Barbara; Hönes, Katharina:
Photoinactivation results of Enterococcus moraviensis with blue and violet light suggest the involvement of an unconsidered photosensitizer,
in: Biochemical and Biophysical Research Communications, Elsevier, 2020, pages 5.
DOI: 10.1016/j.bbrc.2020.09.091, ISSN: 0006-291X
Sieber, Nicole; Kölbl, Philipp; Lingenfelder, Christian; Stucke-Straub, Kathrin; Kupferschmid, Sebastian; Hessling, Martin:
Measurement of the retinal irradiation exposure during diaphanoscopic illumination,
in: Current Directions in Biomedical Engineering 2020;6(3): 20203070, Journal of the German Society for Biomedical Engineering in VDE and the Austrian and Swiss Societies for Biomedical Engineering (ed.), De Gruyter, 2020, pages 4.
DOI: 10.1515/cdbme-2020-3070, ISSN: 2364-550
Sicks, Ben; Hönes, Katharina; Spellerberg, Barbara; Hessling, Martin:
Blue LEDs in Endotracheal Tubes May Prevent Ventilator Associated Pneumonia,
in: Photobiomodulation, Photomedicine, and Laser Surgery, 2020, 38(9), Various Laser Medical Societies (ed.), Mary-Ann-Liebert, 2020, pages 571-576.
DOI: doi.org/10.1089/photob.2020.4842, ISSN: 2578-5478
Hessling, Martin; Spellerberg, Barbara; Hoenes, Katharina:
Potential self-disinfection capacity of touch screen displays,
in: Journal of Biophotonics, Wiley (ed.), Wiley, 2019, pages 1-4.
DOI: 10.1002/jbio.201900118
Hoenes, Katharina; Wenzel, Ulla; Spellerberg, Barbara; Heßling, Martin:
Photoinactivation Sensitivity of Staphylococcus carnosus to Visible Light Irradiation as a Function of Wavelength,
in: Photochemistry and Photobiology, American Society for Photobiology (ed.), Wiley, 2019, pages 1-43.
DOI: 10.1111/php.13168
ISSN: 1751-1097
Hoenes, Katharina; Wenzel, Ulla, Heßling, Martin:
Realization and assessment of a low-cost LED device for contact lens disinfection by visible violet light,
in: Biomedical Engineering / Biomedizinische Technik (BMT) - ahead of print, German Society of Biomedical Engineering (ed.), de Gruyter, 2019, pages 1-6.
DOI: 10.1515/bmt-2019-0231
ISSN: 1862-278X
Schmid, Julian; Hoenes, Katharina; Vatter, Petra; Heßling, Martin:
Antimicrobial Effect of Visible Light - Photoinactivation of Legionella rubrilucens by Irradiation at 450, 470, and 620 nm,
in: Antibiotics, 8(4), 2019, MDPI (ed.), MDPI, 2019, pages 187.
DOI: 10.3390/antibiotics8040187, ISSN: 2079-6382
E. Goldberg-Bockhorn, R. Riepl, U. Wenzel, F. Sommer, M. Wigand, J. Döscher, L. Körber, M. Heßling, T. K. Hoffmann:
Effects of a combined static and dynamic cultivation on the matrix synthesis of chondrocytes,
Laryngo-Rhino-Otologie 98 proceedings, doi: 10.1055/s-0039-1686887, April 2019
P. S. Koelbl, M. Hessling, C. Lingenfelder, S. Kupferschmid: Higher Risk of Light-Induced Retinal Damage Due to Increase of Intraocular Irradiance by Endoillumination. Ophthalmology and Therapy, doi: 10.1007/s40123-018-0157-3, December 2018
K. Hoenes, M. Hess, P. Vatter, B. Spellerberg and M. Hessling: 405 nm and 450 nm Photoinactivation of Saccharomyces cerevisiae. European Journal of Microbiology and Immunology, 8(4):1-7, doi: 10.1556/1886.2018.00023, December 2018
Kast R. E., Skuli N., Sardi I., Capanni F., Hessling M., Frosina G., Kast A. P., Karpel-Massler G., Halatsch M.: Augmentation of 5-Aminolevulinic Acid Treatment of Glioblastoma by Adding Ciprofloxacin, Deferiprone, 5-Fluorouracil and Febuxostat: The CAALA Regimen, Brain Sci. 22(8). pii: E203. doi: 10.3390/brainsci8120203, November 2018
Och, Fabian; Wenzel, Ulla; Hasch, Katja; Goldberg-Bockhorn, Eva; Rotter, Nicole; Hessling, Martin; Munz, Michael: Histological Image Processing for the Assessment of Tissue Engineered Cartilage. Current Directions in Biomedical Engineering, 4(1):461-464, doi: 10.1515/cdbme-2018-0110, September 2018
M. Hessling, P.S. Kölbl, P. Singh, S. Deuchler, D. Sinning, F.H.J. Koch, C. Lingenfelder: Danger from LED light? - A comparative study. The Ophthalmologist, 1-6, doi: 10.1007/s00347-018-0778-x, August 2018
P.S. Koelbl, J.U. Werner, C. Enders, C. Lingenfelder, F.H.J. Koch, M. Hessling: Short-Term Intraocular Pressure Rise during Locally Induced Force by Ophthalmologic Surgery Applications. Ophthalmic Research, 61(3):159-167, doi: 10.1159/000488493, May 2018
P.S. Kölbl, C. Lingenfelder, C.W. Spraul, J. Kampmeier, F.H. Koch, Y.K. Kim, M. Hessling: An intraocular micro light-emitting diode device for endo-illumination during pars plana vitrectomy. European Journal of Ophthalmology, 29(1):75-81, doi: 10.1177/1120672118757618, March 2018
Hessling, M.; Koelbl, P.; Lingenfelder, C.; Sinning, D.; Sing, P.; Deuchler, S.; Koch, F.: LED Illumination - A Hazard to the Eye?Optik&Photonik, 4:40-44, doi: 10.1002/opph.201800029, October 2018
M. Hessling, P. Koelbl, C. Lingenfelder: Device for illuminating the intraocular space, European patent application, October 2018
M. Hessling, J. Schmid, K. Hoenes, P. Vatter: New Legionella Control Options by UV and Violet LEDs for Hospitals and Care Facilities. Hospital Practices and Research, 3(3):76-78, doi: 10.15171/hpr.2018.17, July 2018.
E. Goldberg-Bockhorn, M. Hessling, U. Wenzel, N. Rotter, L. Körber, J. Döscher: Cartilage tissue engineering in the dynamic culture under hypoxic conditions, Laryngo-Rhino-Otology 97 Proceedings, doi: 10.1055/s-0038-1641049, April 2018
P.S. Kölbl, F. H. J. Koch, C. Lingenfelder, M. Hessling: New illumination approaches with single-use micro LEDs endoilluminators for the pars plana vitrectomy. SPIE Proceedings Ophthalmic Technologies XXVIII, 10474:1-9, doi: 10.1117/12.2289110, February 2018
K. Hoenes, K. Wild, J. Schmid, B. Spellerberg, M. Hessling: Microbial photoinactivation by 470 nm radiation: an investigation into the underlying photobiological mechanism. SPIE Proceedings Light-Based Diagnosis and Treatment of Infectious Diseases, 10479:1-9, doi: 10.1117/12.2288346, February 2018
P.S. Koelbl, P. Klante, F. Koch, C. Lingenfelder, J.U. Werner, C. Enders, M. Hessling: Location and pressure dependent transmission of human and porcine sclera. Albrecht von Graefe's Archives of Ophthalmology, doi: 10.1007/s00417-017-3758-y, August 2017
C. Lingenfelder, F. Koch, P. Koelbl, P. Klante, M. Hessling: Transscleral LED illumination pen. Biomed. Eng. Lett. doi: 10.1007/s13534-017-0039-y, June 2017
J. Schmid, K. Hoenes, M. Rath, P. Vatter, B. Spellerberg, M. Hessling: Photoinactivation of Legionella rubrilucens by visible light. European Journal of Microbiology and Immunology, 7(2):146-149, doi: 10.1556/1886.2017.00006, April 2017
F.H.J. Koch, S. Deuchler, P. Singh, M. Hessling: Diaphanoscopy on the eye. The Ophthalmologist, doi: 10.1007/s00347-017-0470-6, April 2017
J. Schmid, K. Hoenes, M. Rath, P. Vatter, M. Hessling: UV-C inactivation of Legionella rubrilucens. GMS Hygiene and Infection Control, 12:1-6, doi: 10.3205/dgkh000291, April 2017
T. Lepiarz, U. Wenzel, M. Munz, K. Hasch, E. Goldberg-Bockhorn, N. Rotter, M. Hessling: Computational Analysis of Histological Images of Tissue Engineered Cartilage for Evaluation of Scaffold Cell Migration. Journal of Biomedical Engineering and Medical Imaging, 4(6):1-12, December 2017
K. Hoenes and M. Hessling: Violet light instead of chemicals - alternative contact lens disinfection. EyeBizz, III(6):38-41, November 2017
U. Wenzel, S. Princz, C. Dettmann, E. Goldberg-Bockhorn, K. Hasch, L. Körber, T. Lepiarz, M. Munz, R. Riepl, N. Rotter and M. Hessling: New cartilage from the reactor - development of a tissue engineering bioreactor for cartilage of the head and neck region. horizonte (Research at the Universities of Applied Sciences in Baden-Württemberg), 50:6-8, October 2017
M. Hessling, J. Feiertag, K. Hoenes: Pathogens provoking most deaths worldwide. Bioscience Biotechnology Research Communications, 10(2):1-7, July 2017
M. Hessling: Device for simple and efficient fluorescence excitation in real-time thermocyclers with one or more LEDs. DPMA utility model application, June 2017
M. Hessling: Device for energy-efficient cyclic heating and cooling of a metal block for use in a thermal cycler, DPMA utility model application, June 2017
M. Hessling, K. Hoenes: Disinfection with visible light - Gentle germ reduction. Biophotonics, 10 (1):26-29, March 2017.
K. Hoenes, M. Hessling: Method for disinfecting or sterilizing medical aids and device for carrying out the method. DPMA patent application, February 2017.
Biosens: Online Analytics in Bioreactors
A. Bogomolov, M. Hessling, U. Wenzel, S. Princz, T. Hellmuth, M. J. Barraza Bernal, T. Sakharova, I. Usenov, V. Artyushenko, H. Meyer: Development and testing of mid-infrared sensors for in-line process monitoring in biotechnology. Sensors and Actuators B: Chemical, doi: 10.1016/j.snb.2015.07.118, August 2015.
S. Princz, U. Wenzel, R. Miller, and M. Hessling: Data pre-processing method to remove interference from gas bubbles and cell clusters during anaerobic and aerobic yeast fermentation in a stirred tank bioreactor. Journal of Applied Spectroscopy, 81 (5):855-861, doi: 10.1007/s10812-014-0017-4, November 2014.
S. Princz, U. Wenzel, H. Tritschler, S. Schwarz, C. Dettmann, N. Rotter and M. Hessling: Automated bioreactor system for cartilage tissue engineering of human primary nasal septal chondrocytes. Biomedical Engineering, - (-) :1-6, doi: 10.1515/bmt-2015-0248, October 2016.
S. Princz, U. Wenzel, S. Schwarz, N. Rotter, and M. Hessling: New bioreactor vessel for tissue engineering of human nasal septal chondrocytes. Current Directions in Biomedical Engineering, doi: 10.1515/cdbme-2016-0071, September 2016.
A. Kuehn, A. Graf, U. Wenzel, S. Princz, H. Mantz, and M. Hessling: Development of a highly sensitive spectral camera for cartilage monitoring. Journal of Sensors and Sensor Systems, doi: 10.5194/jsss-4-289-2015, September 2015.
CleanSpring: Reduction of Legionella in Drinking Water
F. Stangl, A. Gross, K. Hönes, M. Hessling: Biofilms and Nutrient Resorption in Drinking Water, Langenau Water Forum (Poster), November 2015
DNACrack: Water Disinfection Systems for the Developing World
M. Hessling, A. Gross, K. Hoenes, M. Rath, F. Stangl, H. Tritschler, M. Sift: Efficient Disinfection of Tap and Surface Water with a Single High-Power 285 nm LED and Square Quartz Tube. Photonics, 1:1-7, doi: 10.3390/photonics3010007, January 2016
A. Gross, F. Stangl, K. Hoenes, M. Sift, and M. Hessling: Improved Drinking Water Disinfection with UVC-LEDs for Escherichia coli and Bacillus subtilis Utilizing Quartz Tubes as Light Guides. Water, -:4605-4621, doi: 10.3390/w7094605, August 2015
A. Gross, F. Stangl, K. Hoenes, M. Hessling, R. Brucher: Frequency-Controlled Power Ultrasound Unit for Battery-Powered UVC-LED Based Disinfection System. International Journal of Advanced Research in Computer Science and Electronics Engineering, 3 ( 12 ):476-481 ijarcsee.org/index.php/IJARCSEE/article/view/515/485, December 2014
CoLaLight: (Contact Lens) Disinfection with Visible Light
Hessling, M.; Spellerberg, B.; Hoenes, K.: Photoinactivation of bacteria by endogenous photosensitizers and exposure to visible light of different wavelengths - A review on existing data, FEMS Microbiol Lett. 2016 Dec 2., doi: 10.1093/femsle/fnw270
Hoenes, K.; Stangl, F.; Gross, A.; Hessling, M.: Improved contact lens disinfection by exposure to violet radiation. Technol. Health Care. 2016; 24(1):145-51. doi: 10.3233/THC- 151104
SafeLight: Gentle Illumination in Retinal Surgery
M. Hessling, P. S. Koelbl, C. Lingenfelder, F. Koch: Miniature LED endoilluminators for vitreoretinal surgery. Proc. SPIE. 9542, Medical Laser Applications and Laser-Tissue Interactions VII, doi: 10.1117/12.2197603
P. S. Kölbl, C. Lindner, C. Lingenfelder, S. Deuchler, P. Singh, F. Koch, M. Hessling: Fiberless miniature chandelier LED endoilluminator for pars plana vitrectomy. Ophthalmologe. 2016 Jan;113(1):47-51. doi: 10.1007/s00347-015-0050-6
P. S. Kölbl, C. Lindner, C. Lingenfelder, S. Deuchler, P. Singh, F. Koch, M. Hessling: An extraocular non-invasive transscleral LED endoilluminator for eye speculum integration. Graefes Arch. Clin. Exp. Ophthalmol. 2015 Sep; 253(9):1529-35. doi: 10.1007/s00417-015-3036-9
